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Small Study Links Ibuprofen to Testosterone Issues

Men who take over-the-counter ibuprofen might develop problems with testosterone production, according to a small study.

In particular, ibuprofen may affect the “pituitary-testis axis,” a system that involves the pituitary gland in the brain and a man’s testes. The pituitary gland produces a substance called luteinizing hormone, which spurs cells in the testes to start making testosterone.

Classified as a non-steroidal anti-inflammatory (NSAID), ibuprofen is a commonly-used drug used to reduce pain and inflammation.

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