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Treating Diabetes & ED

Avanafil may help diabetic men with erectile dysfunction (ED).

Many men with diabetes have ED. To have an erection firm enough for sex, the penis needs to fill with blood. But diabetes can damage nerves and blood vessels, making erection difficult.

There are several different treatments for ED, but a recent clinical trial has shown promising results for men with diabetes.

The drug is called avanafil and researchers from VIVUS, the drug’s manufacturer, have completed the trial’s third phase. Their results were presented at a recent meeting of the European Association for the Study of Diabetes (EASD).

The trial involved 390 men with type 1 and type 2 diabetes. Their average age was 58 and they had had mild-to-severe ED for over six months. The men took the drug about a half hour before sex.

Researchers tested two different doses of avanafil and compared those results to a placebo.

The men who took 100 mg of avanafil had better results than those who took the placebo. And the men who took 200 mg had the best results of all. For some men, the effects lasted for six hours.

Side effects included headache, sinus congestion, flushing, and common cold symptoms.

Although these results are encouraging, avanafil is not yet available. The U.S. Food and Drug Administration (FDA) recently accepted VIVUS’s new drug application for avanafil and expects to complete its review by the end of April 2012.