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Conditions: Premature Ejaculation

Treating Premature Ejaculation

2. Non-FDA approved treatment options: a number of over-the-counter and prescription 'medications' have been used for PE:

A. Herbal therapies: there are currently no studies that show the effectiveness of herbal products (also known as nutriceuticals). Many of these products contain androgens (testosterone, DHEA and androstenedione) that may be inappropriate for some men to use. Furthermore, some herbal products used for male sexual health contain Viagra and Cialis, which is of concern to men taking nitroglycerin-containing medications, since taking these together can be deadly

B. PDE-5 inhibitors: medications such as Viagra®, Levitra® and Cialis® have been used by some men for PE. Studies suggest that they may help some men suffering from PE. Scientists are not sure why these medications would work in men with PE. However, it is generally believed that these medications can help men with PE who also have ED.

C. Antidepressant medications: Antidepressants have been used for the treatment of PE. Prozac®, Paxil® and Zoloft® have been used with some success for this condition. Although no antidepressants have been specifically used to treat PE, several weeks of treatment with some of these medications has been shown to help many men with PE. Several weeks of treatment is required for these medications to work. The drawbacks of these medications include the need for daily use (when men stop using them they return to having rapid ejaculation), the stigma that they are anti-depressant drugs (for example, airline pilots are not permitted to take these medications and fly) and side effects (drowsiness, nausea, dizziness, dry mouth and a range of sexual problems, such as decreased or increased sexual interest, ejaculation or orgasm problems, and impotence).


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