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Antidepressant Trintellix Has Fewer Sexual Side Effects, Study Finds

In addition, the patients’ improvements with depression were maintained.

"Sexual dysfunction is one of the most common and bothersome side effects patients with depression struggle with when prescribed an SSRI," said lead investigator Dr. Anita Clayton in press statement.

She added, "We designed the study to specifically look at these troublesome side effects. Changing to a medication with potentially fewer sexual side effects, while not losing progress in treating depression, provides an important option for patients with depression."


“Expanded label shows Trintellix effective for SSRI-emergent sexual dysfunction”

(October 25, 2018)

MD Magazine

Rossi, Krista

“Label Update Shows Vortioxetine as Effective for Treatment-Emergent Sexual Dysfunction”

(October 22, 2018)


Han, Da Hee, PharmD

“Vortioxetine Beats Escitalopram in Improving SSRI-Induced Sexual Dysfunction”

(October 22, 2018)

PR Newswire

“New Data Added to TRINTELLIX® (vortioxetine) Labeling Demonstrated Superiority Over Escitalopram in Improving SSRI-Induced Sexual Dysfunction in Patients with Major Depressive Disorder”

(Press statement. October 22, 2018)

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