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Could Erectile Dysfunction Drugs Fight Cancer?

The research was conducted as part of the Repurposing Drugs in Oncology (ReDO) project, which investigates ways that commonly available drugs might be used to fight cancer. Using such medications could eventually make cancer treatment less expensive. In addition, repurposed drugs could have fewer, or less severe, side effects than other cancer drugs.

"In many respects sildenafil is the ultimate repurposing success story," said study co-author Dr. Pan Pantziarka in a press statement. "It was originally developed for angina, repurposed for erectile dysfunction and then again for pulmonary arterial hypertension, and now it has the potential to be repurposed again as an anti-cancer drug."

Resources

Ecancermedicalscience.org

Pantziarka, Pan, et al.

“Repurposing drugs in oncology (ReDO)—selective PDE5 inhibitors as anti-cancer agents”

(Full-text. Published: April 11, 2018)

https://www.ecancer.org/journal/12/full/824-repurposing-drugs-in-oncology-redo-selective-pde5-inhibitors-as-anti-cancer-agents.php

Eurerkalert.com

“Viagra has the potential to be used as a treatment for rare cancers”

(Press release. April 11, 2018)

https://www.eurekalert.org/pub_releases/2018-04/e-vht041118.php

“Why Does Viagra Have the Potential to Treat Rare Cancers?”

(Infographic. April 11, 2018)

https://www.eurekalert.org/multimedia/pub/167675.php

UPI

Cone, Allen

“Study: Viagra may be tested for treatment of rare cancers”

(April 13, 2018)

https://www.upi.com/Study-Viagra-may-be-tested-for-treatment-of-rare-cancers/6611523621682/

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