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Peyronie’s & Dupuytren’s Contracture

About 30% of men with Peyronie’s disease (penile curvature) also develop hardened scar tissue on other parts of the body, most often on the hands and feet. One common condition is Dupuytren’s contracture, which occurs in the hand.

Men with Peyronie’s disease have plaques, or hardened patches of scar tissue, on their penis. These plaques form in the sheath that surrounds the erectile tissue. Because the plaques aren’t flexible, they cause the penis to curve in one direction.

The plaques are not harmful or cancerous. Sometimes the curve isn’t a problem. But for some men, the curve is so severe that sexual intercourse is painful or impossible.

Similarly, Dupuytren’s contracture is a connective tissue disorder that causes scar tissue to thicken and tighten until it forms a cord beneath the palm of the hand. This makes fingers curl. Usually the ring finger has the most difficulty. Some people with Dupuytren’s contracture are unable to extend their fingers at all.

Researchers don’t know what, exactly, causes Peyronie’s disease or Dupuytren’s contracture. Both conditions seem to stem from injuries. For example, a man’s penis might be hurt during sports or vigorous intercourse.

Heredity is another possible similarity. Dupuytren’s contracture can run in families. Some researchers believe that Peyronie’s disease is an inherited condition as well.