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After ADT, Testosterone Levels Don’t Always Recover

After ADT, Testosterone Levels Don’t Always RecoverMany men undergo androgen deprivation therapy (ADT) as part of their prostate cancer treatment. But even two years after ADT ends, patients may still struggle with low testosterone, according a recent report.

The term androgens refer to male hormones like testosterone. This hormone is important for men’s health, but it can also fuel the growth of prostate cancer cells. ADT reduces the amount of testosterone in a man’s body, cutting off the cancer’s power supply.

ADT is more common in men with intermediate- and high-risk prostate cancer as well as men whose cancer has spread beyond the prostate gland.

Decreasing testosterone in this way has its drawbacks, however. Low testosterone is linked to lower bone density, leaving men at higher risk for osteoporosis. Men with low testosterone are also more likely to develop diabetes and heart disease.

There are sexual side effects as well, including diminished libido, orgasm difficulties, and erectile dysfunction.

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