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Peyronie’s Disease: RestoreX Traction Device Investigated With Injection Therapy

Researchers wanted to know how men would fare using a combination of CCH therapy and RestoreX traction. They designed a study involving 113 men with Peyronie’s disease who were divided into three treatment groups:

  • Group 1 (52 men) received CCH injections alone.
  • Group 2 (45 men) received CCH injections and used a traction device other than the RestoreX device.
  • Group 3 (16 men) received CCH injections and used the RestoreX device.

The men ranged in age from 49 to 65. The researchers measured penile curvature and length before the study began and periodically throughout.

Overall, Group 3 (CCH injections and RestoreX) saw the greatest improvements in their Peyronie’s symptoms. Their average curvature improvement was 33.8 degrees, compared to 20.3 degrees for Group 1 (CCH alone) and 19.2 degrees for Group 2 (CCH plus another traction device). They also had greater gains in length, with an average of +1.9 centimeters compared the -0.7 centimeters for Group 1 and -0.4 centimeters for Group 2.

Group 3 used their devices for shorter daily periods as well. Their average use was 0.9 hours a day, while the other groups’ average was 1.9 hours.

“Group 3 was 6.9 times more likely to achieve ≥20° curvature improvement, and 3.5 times more likely to achieve ≥50% curvature improvement, and 10.7 times more likely to experience ≥20% length improvement,” the authors wrote.

“These findings represent the greatest overall curvature improvement achieved using any adjunctive therapy with CCH reported to date,” they added. However, they called for further research to validate their results.

The study was published online in April 2019 as an article in press.


The Journal of Sexual Medicine

Alom, Manaf, MBBS, et al.

“Efficacy of Combined Collagenase Clostridium histolyticum and RestoreX Penile Traction Therapy in Men with Peyronie’s Disease”

(Full-text article in press. Published online: April 4, 2019)

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