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Testosterone Therapy in Aging Men: An Overview of Research

Testosterone Therapy in Aging Men: An Overview of Research Testosterone replacement therapy (TRT) can be a safe and effective way to treat sexual dysfunction in men with age-related low testosterone, according to a recent review of medical studies.

However, TRT is not recommended for other medical conditions, like obesity or mobility issues, the authors said.

As men get older, their testosterone levels gradually decline as a normal part of aging. As a result, sexual drive might start to wane. Men might also start feeling moody and fatigued. Some experience weakness.

Guidelines from medical organizations like the U.S. Endocrine Society, the U.S. Food and Drug Administration (FDA), and Health Canada recommend TRT for men whose testosterone deficiency is caused by “organic” problems in the glands that trigger testosterone production. TRT is generally not recommended for age-related low testosterone.

Still, the number of testosterone prescriptions for age-related testosterone deficiency has increased in North America over the past two decades. With this in mind, the study authors wanted to learn more about TRT and its outcomes in these patients.

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