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On Friday, May 15, during the SMSNA 31st Annual Scientific Program at AUA, Dr. Jessica Yih discussed alternative options for the treatment of low sexual desire in both men and women.
Dr. Yih stresses that low libido and hypoactive sexual desire disorder (HSDD) are extremely common. This can be related to testosterone; however, testosterone may not always be effective in treating these sexual dysfunctions.
Dr. Yih discussed the potential negative side to GLP-1 receptor agonists, as they may impair sexual function across multiple areas, especially low libido and orgasmic disorder. This is likely due to rapid weight loss and serotonergic effects of these medications. '
Scream creams and vaginal estrogen are useful but should be used carefully in treating non-libido-related sexual dysfunction first. Scream creams have inconsistent dosages and may be more difficult to come by.
Bremolanotide is historically used to treat women. However, more men are approaching their clinicians to ask about it. Unfortunately, the intranasal formulation was barred for use with men by the FDA; however, it could be helpful in creating sexual desire and arousal for men and women of all ages. Flinbanserin is approved for HSDD in premenopausal women, but with further investigation may be useful in the future.
Dr. Yih urges clinicians to consider patients' current medication when diagnosing and treating sexual dysfunction. Be aware of GLP-1 medications, be careful with scream creams and vaginal estrogen so as to target their non-libido-related sexual dysfunction, and start prescribing bremolanotide to all patients.
Dr. Yih stresses that low libido and hypoactive sexual desire disorder (HSDD) are extremely common. This can be related to testosterone; however, testosterone may not always be effective in treating these sexual dysfunctions.
Dr. Yih discussed the potential negative side to GLP-1 receptor agonists, as they may impair sexual function across multiple areas, especially low libido and orgasmic disorder. This is likely due to rapid weight loss and serotonergic effects of these medications. '
Scream creams and vaginal estrogen are useful but should be used carefully in treating non-libido-related sexual dysfunction first. Scream creams have inconsistent dosages and may be more difficult to come by.
Bremolanotide is historically used to treat women. However, more men are approaching their clinicians to ask about it. Unfortunately, the intranasal formulation was barred for use with men by the FDA; however, it could be helpful in creating sexual desire and arousal for men and women of all ages. Flinbanserin is approved for HSDD in premenopausal women, but with further investigation may be useful in the future.
Dr. Yih urges clinicians to consider patients' current medication when diagnosing and treating sexual dysfunction. Be aware of GLP-1 medications, be careful with scream creams and vaginal estrogen so as to target their non-libido-related sexual dysfunction, and start prescribing bremolanotide to all patients.
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